Amniotic epithelial cells from the human placenta potently suppress a mouse model of multiple sclerosis.

hAEC treatment led to a reduction in MOG-specific autoantibodies in sera but it failed to reach statistical significance ( Fig. 4C ).

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Splenocytes from hAEC-treated mice appeared to produce less Th1 cytokine IFN-gamma and less inflammatory cytokines GM-CSF and TNF-α; although the reduction did not reach statistical significance ( Fig. 4B ).

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