Construction of a DNA Repair Pathway–Focused Score Kaplan–Meier log-rank P values were calculated to identify a subset of genes whose expression values showed a trend associated with overall survival (OS) ( P < .15) ( Supplementary Figure 1 , available online).
We therefore examined the breakdown of BRCA1 and BRCA2 germline and somatic mutations by scoring category (≤7, 8–13, and ≥14), which corresponded to low, intermediate, and high likelihood of CR (44%, 73%, and 80% likelihood of CR), and found that the percentage of BRCA germline and somatic mutations increased correspondingly (13% germline and 0% somatic mutations for scoring category ≤7, 15% germline and 1% somatic mutations for scoring category 8–13, and 19% germline and 5% somatic mutations for scoring category ≥14), although this did not reach statistical significance (likelihood ratio test P = .18) ( Supplementary Figure 5 , available online).