Apoptosome-dependent caspase activation proteins as prognostic markers in Stage II and III colorectal cancer.

Br J Cancer · 2012 · PMC3341858 · PMID 22481083

Europe PMC DOI

hedged sentences

0.0662

closest p · 1.3× alpha

0.0662

boldest claim

The sentences

approached significanceP =0.0662so close (0.05 < p ≤ 0.1)

In Stage II disease, only strong Pro-caspase 3 expression was associated with better recurrence-free (HR=0.488) and overall survival (HR=0.706); however, this was significant in predicting recurrence ( P =0.0052) and approached significance for overall survival ( P =0.0662) ( Tables 2 and 3 ), indicating that Pro-caspase 3 may be an important independent prognostic marker in Stage II colorectal cancer.

also in 8,237 other papers

did not reach statistical significanceno p-value reported

A previous study of Stage II colorectal cancer reported that APAF1 expression was similarly associated with better prognosis ( Krajewska et al , 2005 ); however, this did not reach statistical significance.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.