Depletion of cytotoxic T-cells does not protect NUP98-HOXD13 mice from myelodysplastic syndrome but reveals a modest tumor immunosurveillance effect.

17/20), and more likely to die with progressive MDS (6/19 vs 3/20) ( Figure 2B ), although these differences did not reach statistical significance (P = 0.20, Two-way ANOVA).

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However, NHD13/Rag1 KO mice had decreased survival and showed a trend toward increased incidence of transformation to AML compared to the NHD13 mice, suggesting protection from AML transformation by a modest immuno-surveillance effect.

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