Conversely, in a cohort of patients that had been treated with radiotherapy alone, STAT6 expression showed a clear trend towards a poor clinical outcome, which could be explained by the immune-evasive potential of STAT6-expressing tumor cells, if not attacked by platinum.
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The sentences
Similarly, in a cohort of 70 patients with ovarian cancer, the majority of the tumors were negative or weakly positive and although PD-L2 expression was correlated with an impaired survival, this did not reach statistical significance [ 63 ].