Identification of sialyltransferase 8B as a generalized susceptibility gene for psychotic and mood disorders on chromosome 15q25-26.

PLoS One · 2012 · PMC3364966 · PMID 22693595

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.1290

boldest claim

The sentences

nominally significantP <0.05actually significant

Nominally significant association ( P <0.05) was found with 18 SNPs, in three main clusters across three adjacent genes SLCO3A1 , ST8SIA2 , and C15orf32 ( Table 1 ).

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did not reach statistical significanceP = 0.129not close (p > 0.1)

This haplotype also showed the same direction of effect in the NIMH cases with schizophrenia compared to controls (frequency = 0.421 vs 0.396), although it did not reach statistical significance (χ 2 = 2.3, df = 1, P = 0.129, OR = 1.09).

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