On the other hand, the improvement in insulin sensitivity failed to reach statistical significance.
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Effects of gevokizumab on glycemia and inflammatory markers in type 2 diabetes.
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The sentences
The decrease from baseline in mean glycated hemoglobin in the high-dose group (0.3, 1.0, and 3.0 mg/kg) did not reach statistical significance after 1, 2, or 3 months, respectively, consistent with the U-shaped dose-response curve.