Over-expression of monoacylglycerol lipase (MGL) in small intestine alters endocannabinoid levels and whole body energy balance, resulting in obesity.

PLoS One · 2012 · PMC3429419 · PMID 22937137

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0.0700

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showed a trendp = 0.07so close (0.05 < p ≤ 0.1)

At 3 months of age, there was no significant difference in body weights, although the iMGL mice showed a trend toward higher body weight (wild type; 29.1±0.5g vs. iMGL; 30.4±0.5g, p = 0.07).

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did not reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

In fact, fasting leptin levels were 2.5-fold lower in the transgenic animals, although this observation did not reach statistical significance ( Fig.5 , p = 0.07).

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