highly significantP < 0.001
The ANOVA revealed a highly significant difference in 2 h HPF intake in the 4 groups of rats ( F (3, 26) = 19.32; P < 0.001).
The ANOVA revealed a highly significant difference in 2 h HPF intake in the 4 groups of rats ( F (3, 26) = 19.32; P < 0.001).
Following the highest dose of 500 mg/kg of Hypericum perforatum extract, a marked trend to the reduction of HPF intake was observed, but the difference was not statistically significant.
While suppressing the increase in HPF intake in the R + S group, the three doses tested of Hypericum perforatum extract did not significantly reduce HPF in the control group (NR + NS) even if a clear trend of reduction was shown by the highest tested dose (500 mg/kg).