Human monocytes differentiate into dendritic cells subsets that induce anergic and regulatory T cells in sepsis.

PLoS One · 2012 · PMC3468528 · PMID 23071758

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did not reach statistical significanceno p-value reported

In contrast, increased proliferation induced by CD1a+ mDC from patients did not reach statistical significance.

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showed a trendno p-value reported

They showed a trend to generate a low but consistently detected IFN-γ production, suggesting overall reduced regulatory abilities and the emergence of a mild pro-inflammatory potential in this DC subset from patients.

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