Caprylic triglyceride as a novel therapeutic approach to effectively improve the performance and attenuate the symptoms due to the motor neuron loss in ALS disease.

PLoS One · 2012 · PMC3492315 · PMID 23145119

Europe PMC DOI

hedged sentences

0.1650

closest p · 3.3× alpha

0.1650

boldest claim

The sentences

did not reach statistical significancep = 0.165not close (p > 0.1)

Although it was longer than the median survival of SOD1-G93A animals on control diet (129 days), it did not reach statistical significance (Mantel-Cox test, p = 0.165).

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showed a trendno p-value reported

Following caprylic triglyceride treatment, spare respiratory capacity remained unchanged in WT mice and showed a trend for increase in SOD1-G93A mice which did not reach statistical significance ( Fig. 5C ).

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