The only exception was the group with R848 that, although showing a positive trend, did not reach statistical significance ( Figure 4C ).
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Evaluation of TLR agonists as potential mucosal adjuvants for HIV gp140 and tetanus toxoid in mice.
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The sentences
While a number of candidate adjuvants in this study showed a trend towards enhanced systemic responses by SL-immunisation over antigen alone, this was only significant for Poly I∶C with gp140.