Genotypic and phenotypic analysis of familial male breast cancer shows under representation of the HER2 and basal subtypes in BRCA-associated carcinomas.

BMC Cancer · 2012 · PMC3561656 · PMID 23146383

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.0580

boldest claim

The sentences

a strong trendp=0.058so close (0.05 < p ≤ 0.1)

A further 8 (13.3%) IDC-NST had foci of micropapillary differentiation, with a strong trend for co-occurrence in BRCA2 carriers (p=0.058).

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did not reach statistical significanceno p-value reported

There was a trend towards BRCA2 tumours having an invasive micropapillary component (24% 6/25, p=0.0574) and high Bloom Richardson Ellis (BRE) grade for BRCA1 tumours (100% grade 3 3/3, p=0.0855), however these observations did not reach statistical significance.

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