Effects of exenatide and liraglutide on heart rate, blood pressure and body weight: systematic review and meta-analysis.

BMJ Open · 2013 · PMC3563145 · PMID 23355666

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did not reach statistical significanceno p-value reported

Exenatide twice daily increased the heart rate by 0.82 bpm (−0.15 to 1.79) versus active control and by 0.88 bpm (−0.47 to 2.22) versus placebo, which did not reach statistical significance ( figure 3 ).

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failed to reach statistical significanceno p-value reported

Reduction in diastolic blood pressure failed to reach statistical significance (−0.54 mm Hg (−1.15 to 0.07) vs placebo and −0.50 mm Hg (−1.24 to 0.24) vs active control).

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highly significantno p-value reported

We confirm a small but highly significant reduction in body weight as a result of GLP-1 therapy.

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