Gene expression analyses implicate an alternative splicing program in regulating contractile gene expression and serum response factor activity in mice.

PLoS One · 2013 · PMC3577904 · PMID 23437181

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0.0600

closest p · 1.2× alpha

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boldest claim

The sentences

did not reach statistical significanceP = 0.06so close (0.05 < p ≤ 0.1)

Although the increases in mean Ctgf and Fos transcript levels did not reach statistical significance (P = 0.06 and 0.07 for Ctgf in the mild and severe line, respectively, and P = 0.14 and 0.18 for Fos ), this is likely due to higher levels of variability for these transcripts.

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showed a trendno p-value reported

Two additional SRF targets ( Ctgf and Egr1 ) showed a trend towards decreased expression in the MCKCUG-BP1 heart, but did not reach statistical significance.

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