Acute SIV infection in sooty mangabey monkeys is characterized by rapid virus clearance from lymph nodes and absence of productive infection in germinal centers.

PLoS One · 2013 · PMC3589484 · PMID 23472105

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closest p · 2.2× alpha

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did not reach statistical significancep = 0.11not close (p > 0.1)

When the two CD8-depleted SM were excluded from the analysis, SM showed a trend towards lower overall LN virus burden at 2 wpi compared with PM, but this difference did not reach statistical significance (p = 0.11, MWU; data not shown).

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showed a trendno p-value reported

SM and PM had comparable follicular (B lymphocyte) and GC area measurements at baseline and at 2 weeks post-inoculation (wpi) with SIV ( Figure 1B, C ) ; however, by 6 wpi, SM showed a trend towards greater Ki67 + GC area and had significantly greater numbers of apoptotic cells (caspase 3 + ) within GC as compared to PM at a similar time post-inoculation ( Fig. 1C , p = 0.035).

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