Can certain genotypes predispose to poor asthma control in children? A pharmacogenetic study of 9 candidate genes in children with difficult asthma.

PLoS One · 2013 · PMC3616093 · PMID 23573270

Europe PMC DOI

hedged sentences

0.0330

closest p · 0.7× alpha

0.0330

boldest claim

The sentences

nominally significantp = 0.033actually significant

Analysis of the allelic distribution among patients according to their asthma severity also indicated nominally significant associations of allele A of IL-4Rα A1199>C, allele T of IL-4Rα T1570>C and allele A of TNFα TNFα C-863>A with asthma severity (p = 0.033, p = 0.018 and p = 0.047, respectively).

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did not reach statistical significanceno p-value reported

However, these associations did not reach statistical significance after correction for multiple testing.

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