Early vessel destabilization mediated by Angiopoietin-2 and subsequent vessel maturation via Angiopoietin-1 induce functional neovasculature after ischemia.

PLoS One · 2013 · PMC3628915 · PMID 23613948

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0.0800

closest p · 1.6× alpha

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The sentences

a strong trendp = 0.08so close (0.05 < p ≤ 0.1)

Of note, we found a strong trend towards improvement of perfusion (0.80±0.04 LDI ratio (r/l), p = 0.08) ( Fig. 4A,B ) in the rAAV.APLN+Ang2 (d0-3) group, which co-incided with improved CMF-R (1.59±0.02) compared to rAAV.APLN only and improved PC-R (0.67±0.01), compared to rAAV.APLN+Ang2 ( Fig. 4C–E ).

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showed a trendno p-value reported

The combination of hVEGF and Ang2 even further decreased pericyte covarage and thereby showed a trend to a lower perfusion than the hVEGF alone.

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