HPV prevalence and genetic predisposition to cervical cancer in Saudi Arabia.

Infect Agent Cancer · 2013 · PMC3658889 · PMID 23642098

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.2800

boldest claim

The sentences

showed a trendP = 0.06so close (0.05 < p ≤ 0.1)

In addition, statistical analysis showed a trend towards an association between TP53 G72C SNP genotype and HPV infection ( P = 0.06; Table 3 ).

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borderline significantP = 0.07so close (0.05 < p ≤ 0.1)

Furthermore, testing for deviation from HWE also showed a borderline significant deviation ( P = 0.07) for HPV-positive cases, meanwhile no significant deviation was observed for HPV-negative controls.

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did not reach statistical significanceP = 0.28not close (p > 0.1)

Indeed, the analysis of this nested case–control study shows that 93% (13/14) of patients with homozygous variant alleles ( A/A ) are HPV-positive compared to 82% (27/33) in heterozygous and 79% (42/53) in majority allele ( G/G ), suggesting a trend toward an association between the HPV-positivity and XRCC1 G399A genotype; however, it did not reach statistical significance ( P = 0.28; Table 3 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.