Barely Significant
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Fitness costs of mutations at the HIV-1 capsid hexamerization interface.

PLoS One · 2013 · PMC3681919 · PMID 23785468

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closest p · 1.4× alpha
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did not reach statistical significancep = 0.072so close (0.05 < p ≤ 0.1)
However, when restricted to the sites included in this study, the interface sites tended to be slightly more conserved than non-interface sites but the difference did not reach statistical significance (Wilcoxon rank sum test p = 0.072) ( Table S3 ).

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showed a trendno p-value reported
Three mutants: R154K, T110N, and L6I, also showed a trend of reduced fitness, although not significantly different from the prototype (95% CI p>0.05).

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