Genetic Association of Peptidoglycan Recognition Protein Variants with Inflammatory Bowel Disease.

PLoS One · 2013 · PMC3686734 · PMID 23840689

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

approaching significanceP = 0.06so close (0.05 < p ≤ 0.1)

PGLYRP4 exon 2, c.37A>C Ile13Leu, exon 6 c.575G>T Gly188Val, and exon 9, c.*416A>C, UTR variants may associate with CD or with gender in CD patients PGLYRP4 exon 2, c.37A>C, Ile13Leu (SNP rs30006458), was differentially distributed in CD females compared with CD males and the AA genotype was approaching significance ( P = 0.06, Table S16 ).

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approached significanceno p-value reported

Subsequently, only those markers that were significant or approached significance in this initial study were tested in the remaining CD and population control samples and in the CD family controls.

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