Bone Marrow Stem Cell Treatment for Ischemic Heart Disease in Patients with No Option of Revascularization: A Systematic Review and Meta-Analysis.

PLoS One · 2013 · PMC3686792 · PMID 23840302

Europe PMC DOI

hedged sentences

0.1300

closest p · 2.6× alpha

0.1600

boldest claim

The sentences

did not reach statistical significanceP = 0.13not close (p > 0.1)

Pooled evidence across studies using a random effects model showed a lower NYHA class at the end of the trial in patients who received BMSC compared with controls, although this difference did not reach statistical significance (MD −0.56; 95% CI −1.29 to 0.17; P = 0.13).

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failed to reach statistical significanceP = 0.16not close (p > 0.1)

Meta-analysis of the four trials which reported myocardial infarction in at least one of the treatment arms showed a reduced risk of myocardial infarction associated with BMSC although this failed to reach statistical significance (RR 0.55; 95% CI 0.24 to 1.27; P = 0.16).

also in 6,035 other papers

highly significantno p-value reported

A study which evaluated the correlation (Pearson's correlation coefficient, r) between MLHF questionnaire and Seattle Angina Questionnaire showed a highly significant correlation between these measures in patients with both angina (r = 0.826) and HF (r = 0.821) [28] .

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