Barely Significant
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RANK/RANK-L/OPG in patients with bone metastases treated with anticancer agents and zoledronic acid: a prospective study.

Int J Mol Sci · 2013 · PMC3709696 · PMID 23702841

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a clear trendno p-value reported
Conclusions In conclusion, the present prospective study highlights a clear trend towards a decrease in the RANK-L/OPG ratio and NTX levels after 12 months of treatment with zoledronic acid.

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