By 40 weeks after irradiation, the mRNA levels of endoglin were decreased to <50% of control values in both strains, although this did not reach statistical significance.
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Endoglin haplo-insufficiency modifies the inflammatory response in irradiated mouse hearts without affecting structural and mircovascular changes.
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The sentences
PDGF showed a trend to increase in Eng +/+ mice at early times (4 weeks), with increases in both strains at later times ( Figure 5 ).