Gpr3 stimulates Aβ production via interactions with APP and β-arrestin2.

PLoS One · 2013 · PMC3771882 · PMID 24069330

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

Knockdown of βarr2 in WtAPP-HEK cells showed a trend toward reducing Aβ production when co-transfected with GPR3 (1.65+/−0.05 versus 1.93+/−0.10 fold for GPR3 plus control shRNA), but this did not reach statistical significance ( Figure 1F ).

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