Vascular endothelial growth factor receptor inhibitor SU5416 suppresses lymphocyte generation and immune responses in mice by increasing plasma corticosterone.

PLoS One · 2013 · PMC3774642 · PMID 24066177

Europe PMC DOI

hedged sentences

0.0900

closest p · 1.8× alpha

0.1200

boldest claim

The sentences

did not reach statistical significancep = 0.09so close (0.05 < p ≤ 0.1)

This decreased frequency of pro/pre B cells correlated with a 28% decrease in the total number of these cells although this did not reach statistical significance (p = 0.09, Fig. 3B ).

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showed a trendp = 0.12not close (p > 0.1)

Specifically, 7 days following immunization, vehicle-treated control mice showed a trend toward a greater DNP-specific IgM response than that of SU5416-treated mice (p = 0.12, Fig. 6B ).

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