Influence of DNMT genotype on global and site specific DNA methylation patterns in neonates and pregnant women.

Although the current findings of increased IGFBP3 methylation with carriage of the minor rs2424913 variant are consistent with the hypothesis, they did not reach statistical significance following correction for multiple testing.

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Corrections were applied post hoc when interpreting the results to assess whether nominally significant observations were robust to correction for multiple testing.

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