Upregulated microRNA-155 expression in peripheral blood mononuclear cells and fibroblast-like synoviocytes in rheumatoid arthritis.

Clin Dev Immunol · 2013 · PMC3789322 · PMID 24151514

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

did not reach statistical significanceP = 0.053so close (0.05 < p ≤ 0.1)

Increased miR-155 expression was observed in RA PBMC compared with normal controls ( n = 26, 23, resp.), though the difference between them did not reach statistical significance ( P = 0.053, Figure 1(a) ). 3.3.

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an obvious trendno p-value reported

Although no statistical significance was reached, we observed an obvious trend of upregulation of miR-155 after treatment of RA-FLS with TNF- α .

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a significant trendno p-value reported

In comparison with the NC control, there was a significant trend of decrease in IKBKE mRNA levels in cells transfected with miR-155 and increase in IKBKE mRNA level when miR-155 was inhibited ( Figure 8(b) ), although no statistical significance was reached.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.