An investigation into "two hit" effects of BDNF deficiency and young-adult cannabinoid receptor stimulation on prepulse inhibition regulation and memory in mice.

Two weeks after treatment had ceased and animals were tested for baseline locomotor activity without drug injections, male wild-type and HET mice treated previously with CP showed a strong trend for reduced distance traveled [ F (1, 50) = 4.0; P = 0.051].

also in 5,725 other papers

In contrast, in HET mice, CP binding was significantly up-regulated [ F (1, 18) = 6.5; P = 0.020] and this effect appeared to be greatest in male mice (Figure 8 ) although the sex × CP term did not reach statistical significance.

also in 111,027 other papers