Myocardial regeneration by transplantation of modified endothelial progenitor cells expressing SDF-1 in a rat model.

J Cell Mol Med · 2012 · PMC3823424 · PMID 22288686

Europe PMC DOI

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did not reach statistical significanceP < 0.05actually significant

Intracoronary injection showed a trend towards improved LVDP but did not reach statistical significance (LVDP: after EPC-TX 128.9 ± 14.7 mmHg versus LV-SDF-1-EPC 121.1 ± 24.5 mmHg versus control 111.8 ± 19.4 mmHg, P < 0.05, Fig. 5 B).

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highly significantP < 0.05actually significant

Medium SDF-1 levels compared to control medium of non-infected EPCs were highly significantly elevated (LV-SDF-1 infected cells 379.4 ± 118 pg/ml versus 39.4 ± 6.7 pg/ml for non-infected EPC, P < 0.05, Fig. 1 B).

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showed a trendno p-value reported

Although the LV-SDF-1-EPC transplanted hearts showed a trend towards better contractility there was no significant difference between EPC and EPC/SDF-1 groups regarding this parameter.

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