The association between dietary flavonoid and lignan intakes and incident type 2 diabetes in European populations: the EPIC-InterAct study.

A borderline significant trend was seen for theaflavins (HR 0.83 [95% CI 0.69–1.01]; P for trend 0.084).

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Among two Asian studies, the Singapore Chinese Health Study reported an inverse association of diabetes with soy intake and an inverse borderline significant association with isoflavone intake ( 12 ), whereas the Japan Public Health Centre-Based Prospective Study observed no significant association between soy or isoflavone intakes and type 2 diabetes in the whole population; however, among overweight Japanese women there was an inverse association ( 13 ).

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A significant trend was also detected for total flavonoids (HR 0.90 [95% CI 0.77–1.04]; P for trend 0.040).

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