Perioperative therapy for locally advanced gastroesophageal cancer: current controversies and consensus of care.

There was a significant trend to having fewer patients in the advanced T-stage (p = 0.002) and N + groups (p = 0.01) within the perioperative chemotherapy group, despite randomization.

also in 9,775 other papers

Recently, the final results were reported, where the primary endpoint of DFS revealed that UFT was inferior to S-1 (HR 1.23, 1.07-1.43), and that there was a nonsignificant trend (HR 0.92, 0.8-1.07; p = 0.23) to improved DFS with sequential PTX→FP versus FP alone [ 45 ].

also in 5,406 other papers

The trial showed a trend towards improvement in 3 year OS with induction chemotherapy followed by CRT (47 vs. 28%, respectively) but it was not statistically significant (HR 0.67, CI 0.41-1.07, p = 0.07).

also in 53,322 other papers