Although our results did not reach statistical significance, they suggest that patients with consistent retroviral quiescence lack broad polyclonal cellular responses against HIV, whereas patients with retroviral replication tend to form CD8 + lymphocytes against several different HIV pentamers.
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HIV-Specific CD8(+) T Lymphocytes in Blood of Long-Term HIV-Infected Hemophilia Patients.
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The sentences
However, patient profiles based on irregular investigations showed a trend that polyclonality of the cellular anti-HIV response was associated with retroviral load, because strong and broad CD8 + lymphocyte responses against HIV pentamers were more frequently observed in patients with consistently detectable HIV-1 load.