Protein quality and the protein to carbohydrate ratio within a high fat diet influences energy balance and the gut microbiota in C57BL/6J mice.

However, the body composition and body weight in the HFD-WPI group does not appear to reflect a positive energy balance, as animals showed a trend towards a reduction in fat mass and increased lean mass.

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In parallel HOMA-IR values were also reduced ( P< 0.05), but the change in plasma insulin concentration did not reach statistical significance ( Table 2 ).

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