Human TP53 polymorphism (rs1042522) modelled in mouse does not affect glucose metabolism and body composition.

Sci Rep · 2014 · PMC3923217 · PMID 24522546

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

did not reach statistical significancep = 0.08so close (0.05 < p ≤ 0.1)

Mesenterial fat showed a trend towards less increase during ageing in P/P compared to R/R mice, but this did not reach statistical significance (p = 0.08 for age-by-genotype interaction).

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a weak trendno p-value reported

Furthermore, P/P mice showed a weak trend towards the most modest increase in perirenal and epididymal fat depots, but this was far from significant ( p = 0.40 and p = 0.29 respectively for age-by-genotype interaction).

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borderline significantno p-value reported

We did observe a borderline significant delay in fasting glucose levels P/P carrying mice during ageing but this was only at base line (0 minutes) before glucose load.

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showed a trendno p-value reported

Mesenterial fat showed a trend towards less increase during ageing in P/P compared to R/R mice, but this did not reach statistical significance (p = 0.08 for age-by-genotype interaction).

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