Meglumine exerts protective effects against features of metabolic syndrome and type II diabetes.

In further support of these observations, a qualitative ranking of the severity of kidney pathology showed a trend in the ability of meglumine to ameliorate nephritis, hydronephrosis, atrophy-fibrosis and glomerulosclerosis in female mice ( Table 1 ).

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While we did not explore stamina at longer treatment times, starting at 22 weeks we observed a significant trend toward lower weight in meglumine-treated mice compared to control mice receiving plain water ( Fig. 2C ).

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