Albeit only nominally significant ( Figure 2 ) for the single pathway member, multiple intermediates of the AA metabolism were elevated ( Figure 3A , orange pathway): first, DHA, an ω-3 fatty acid, also called cervonic acid; as DHA is an inhibitor of prostaglandin synthase [29] , this probably displays a counter-regulatory - albeit insufficient - mechanism of MUHO's adipocytes.
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Metabolic signatures of cultured human adipocytes from metabolically healthy versus unhealthy obese individuals.
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The sentences
As expected, adiponectin levels were reduced in the IR subjects, but this difference did not reach statistical significance.