Pubertal high fat diet: effects on mammary cancer development.

While pathway analysis did not identify any canonical pathways to a high level of significance, chemotaxis of eosinophils was identified as a highly significant function ( P = 6.4 × 10 -5 ) (see Additional file 7 ), and eosinophil levels correlated well with RNAs for all of the aforementioned chemokines and cytokine (see Additional file 11 ).

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Although HFD caused a 1.8-fold increase in tumor incidence (LFD, 14.95%, n = 87 mice versus HFD, 26.3%, n = 95 mice; P = 0.059), this did not reach statistical significance.

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Tumors showed a trend toward increased Fgf15 expression.

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