Human papillomavirus and p53 expression in cancer of unknown primary in the head and neck region in relation to clinical outcome.

Cancer Med · 2014 · PMC3987086 · PMID 24510528

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.1300

boldest claim

The sentences

did not reach statistical significanceP = 0.053so close (0.05 < p ≤ 0.1)

This difference, however, did not reach statistical significance ( P = 0.053, log-rank test).

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failed to reach significanceP = 0.130not close (p > 0.1)

67 years), although this difference failed to reach significance ( P = 0.130), showing a similar trend as in OSCC, where patients with HPV-positive OSCC usually are younger than those with HPV-negative OSCC 9 , 16 .

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failed to reach statistical significanceno p-value reported

There was a correlation between smoking history and p53 overexpression ( P = 0.021), while all other characteristics failed to reach statistical significance, although a tendency was demonstrated between being HPV DNA+ in the metastases and absent/intermediary-low p53 expression ( P = 0.118).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.