Genome-wide association scan for variants associated with early-onset prostate cancer.

Twenty-three out of 39 SNPs were at least nominally significant (p<0.05) in the current study; all 23 had directions of effect consistent with the previous reports.

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While there was a slight increase in frequency of the rs7225566 risk allele in the JHU data (11% in cases versus 10% in controls), the result did not reach statistical significance.

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