Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes neuroprotection in conscious hypertensive rats.

PLoS One · 2014 · PMC3994132 · PMID 24752645

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failed to reach statistical significanceno p-value reported

Although at 3 days post-stroke the trend for behavioural protection was still evident in these animals, this failed to reach statistical significance.

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did not reach statistical significanceno p-value reported

There was also a trend for C21 to decrease striatal infarct volume but this did not reach statistical significance.

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