Association of the common genetic polymorphisms and haplotypes of the chymase gene with left ventricular mass in male patients with symptomatic aortic stenosis.

Interestingly, one study showed a minor trend of the G allele of rs1800875 toward a lower LVM/BSA in an additive genetic model in all patients, but the difference did not reach statistical significance (p = 0.27).

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However, after indexation to BSA, this difference disappeared in our as well other studies [29] , although one study showed a trend toward higher LVDD/BSA values in women compared with men [28] .

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