Barely Significant
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Comparative efficacy of inhaled corticosteroid and long-acting beta agonist combinations in preventing COPD exacerbations: a Bayesian network meta-analysis.

Int J Chron Obstruct Pulmon Dis · 2014 · PMC4026563 · PMID 24872685

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showed a trendno p-value reported
Although most of the combination therapy showed a trend toward decreased incidence of severe exacerbations, the difference did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.