Filaggrin gene mutation c.3321delA is associated with various clinical features of atopic dermatitis in the Chinese Han population.

PLoS One · 2014 · PMC4032331 · PMID 24858702

Europe PMC DOI

hedged sentences

0.0560

closest p · 1.1× alpha

0.0560

boldest claim

The sentences

showed a trendP = 0.056so close (0.05 < p ≤ 0.1)

The patients harboring c.3321delA (homozygous and heterozygous) displayed a trend of earlier age of onset (0.16 and 0.81 years, respectively) compared with the wild-type genotype (1.07 years), which although displayed no statistical significance but showed a trend among three groups ( P = 0.056) ( Table 4 ) .

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a clear trendno p-value reported

The association of c.3321delA in our group was best described with an additive model that displayed a clear trend for increased disease risk in heterozygous and homozygous c.3321delA patients.

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