Altered formalin-induced pain and Fos induction in the periaqueductal grey of preadolescent rats following neonatal LPS exposure.

PLoS One · 2014 · PMC4039471 · PMID 24878577

Europe PMC DOI

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0.1750

closest p · 3.5× alpha

0.1750

boldest claim

The sentences

failed to reach significancep = .175not close (p > 0.1)

There was a trend towards increased levels of Fos immunoreactivity in the PVT in neonatal saline-treated animals compared to LPS-treated animals, however this failed to reach significance ( p = .175) ( Table 2 ).

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did not reach statistical significanceno p-value reported

Interestingly, although there was a strong trend towards reduced Fos-protein expression in the LPAG in LPS-treated rats, this did not reach statistical significance, possibly due to the lack of power in our analyses.

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a strong trendno p-value reported

In the LPAG, LMM analysis revealed a strong trend towards decreased Fos-positive neurons in LPS-treated rats, however this did not reach significance ( p = .062; Figure 2F ).

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