Integrated pathway-based approach identifies association between genomic regions at CTCF and CACNB2 and schizophrenia.

PLoS Genet · 2014 · PMC4046913 · PMID 24901509

Europe PMC DOI

hedged sentences

0.0970

closest p · 1.9× alpha

0.0970

boldest claim

The sentences

showed a trendp = 0.0970so close (0.05 < p ≤ 0.1)

While CACNB2 showed a trend towards association in an independent dataset from Denmark (p = 0.0970), thus supporting the strong signal from the PGC data, CTCF was found to be strongly associated in the same independent Danish sample (p = 0.0075).

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nominally significantno p-value reported

Two of the eight most frequent genes in the top 14 pathways were also among the nominally significant genes in the gene-based FORGE analysis, i.e.

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