Periaortic brown adipose tissue as a major determinant of [¹⁸F]-fluorodeoxyglucose vascular uptake in atherosclerosis-prone, apoE-/- mice.

Although not significant, a strong trend towards lower activity in Group C, anesthetized and propranolol-treated animals maintained at 37°C was also observed in comparison with Group A ( P = 0.09 and 0.07 for the aortic arch and thoracic aorta, respectively).

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Although lower FDG aortic activity was also observed in Group C than in Group A, the difference did not reach statistical significance most likely due to the fact that propranolol treatment in Group C animals induced a transient increase in glycemia that might have favored FDG uptake by glucose utilizing tissues (see Metabolic condition and FDG biodistribution above).

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