Plasma autoantibodies against heat shock protein 70, enolase 1 and ribonuclease/angiogenin inhibitor 1 as potential biomarkers for cholangiocarcinoma.

PLoS One · 2014 · PMC4109983 · PMID 25058392

Europe PMC DOI

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closest p · 0.0× alpha

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a significant trendP <0.001actually significant

Interestingly, when correlation of HSP70 autoantibody level and disease was analyzed across healthy controls, cholangitis and CCA group using Spearman's rank correlation, HSP70 autoantibody levels manifested a significant trend (r = 0.679, P <0.001).

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failed to reach statistical significanceno p-value reported

Further, plasma ENO1 and RNH1 autoantibodies were higher in CCA compared to cholangitis but failed to reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.