Effects of fentanyl on procedural pain and discomfort associated with central venous catheter insertion: A prospective, randomized, double-blind, placebo controlled trial.

More patients from fentanyl group (4/26) experienced episodes of SpO 2 < 92%, compared with placebo group (0/25), but the difference did not reach statistical significance [ Table 2 ].

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Though fentanyl generally trended towards better discomfort score than placebo, these failed to reach statistical significance except at the end of procedure.

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