Immunodominance and functional alterations of tumor-associated antigen-specific CD8+ T-cell responses in hepatocellular carcinoma.

Of note, due to the small number of patients with responses to three or four TAA, the contribution of these subgroups failed to reach statistical significance while still showing a trend for improved survival over patients without responses (Supporting Fig. 1).

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Similarly, TAA‐specific responses in CD8 + T cells derived from TIL were weaker than those derived from PBMC, although this trend did not reach statistical significance.

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